# Chemical compatibility

Your BactoBox® setup consists of various materials. We choose these materials to ensure wide-ranged chemical compatibility.

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### BactoBox® is compatible with all of SBT's own [chemicals and liquids](/encyclopedia/item-register/vials-flasks-and-liquids.md)

Use SBT's own [Disinfection vial](/encyclopedia/item-register/vials-flasks-and-liquids/disinfection-vial.md) and [Deep clean vial](/encyclopedia/item-register/vials-flasks-and-liquids/deep-clean-vial.md) for [maintenance purposes](/protocols/maintenance.md).
{% endhint %}

## Third party chemicals

If your use cases requires a third party chemical, we can not guarantee chemical compatibility.

We advice you to consult the list of [wetted materials](#wetted-materials) below and make your own chemical compatibility assessment.

Please [reach out to SBT](/troubleshooting/contact-our-support-team.md) for instructions on performing a worst-case exposure test.

{% hint style="danger" %}

### Use of third party chemicals voids the warranty

Your third party chemical may irreparably damage your BactoBox® setup.
{% endhint %}

### Limit exposure

If the worst-case exposure test does not lead to damage if critical components, you should still follow the below recommendations to limit exposure.

* Use the smallest concentration possible
* Expose your BactoBox® setup for the shortest amount of time

{% hint style="success" %}

### Use a [Disinfection vial](/encyclopedia/item-register/vials-flasks-and-liquids/disinfection-vial.md) afterwards

Run the *Clean* program with a [Disinfection vial](/encyclopedia/item-register/vials-flasks-and-liquids/disinfection-vial.md) to wash out any remnants of your third party chemical.
{% endhint %}

## Wetted materials

Below is an *incomplete* list of [wetted materials](#user-content-fn-1)[^1] in your BactoBox® setup.

**Some materials in BactoBox® are part of SBT's intellectual property. Therefore, we can not mention *****all***** materials.**

You can use this list to rule out chemicals. However, you can not use this list to definitely answer questions about chemical compatibility.

| Wetted material                             | Items                         |
| ------------------------------------------- | ----------------------------- |
| Stainless steel                             | Barbs, connectors, tubing kit |
| Silicone                                    | Pulsation damper              |
| Polyphenylsulphone (PPSU)                   | Pulsation damper              |
| Nylon                                       | Filters                       |
| Polypropylene (PP)                          | Barbs, connectors, filters    |
| Ethylene propylene diene monomer (EPDM)     | Flow cell                     |
| Thermoplastic vulcanizate (TPV)             | Tubing kit                    |
| Pharm-A-Line™ thermoplastic elastomer (TPE) | Pump tubing                   |
| Masterflex® Chem-Durance®                   | Tubing kit                    |

## Chemicals NOT compatible with BactoBox®

Below is an *incomplete* list of third party chemicals that are **NOT** compatible with BactoBox®. Concentrated and diluted solutions of these chemicals may cause irreversible damage to the BactoBox® setup. Do not use these.

* Sodium hypochlorite (bleach)
* Mucasol
* Alkaline solutions exceeding pH 10

[^1]: Materials on the flow path that comes in contact with the liquid.


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