comment-questionWhy use BactoBox®

The short answer: Because BactoBox® measures real bacterial growth. No proxies. No guesswork.

BactoBox® helps whether you are trying to:

BactoBox® fits into all key steps in your upstream bioprocess: 🌱 Seed, 🌿 growth, and 🌽 harvest.

With and without BactoBox®

Once you use BactoBox® in your workflows, it's easy to forget what life was like before. This table serves as a reminder.

Workflow
Without BactoBox®
With BactoBox®

Optimize starter culture ⚙️ Optimization 🌱 Seed

TODO

One-shot setup of high quality culture (OptiSeeding)

Inoculate an overnight culture ⚙️ Optimization 🌱 Seed

Track growth curve 💡 Insight 🌿 Growth

Use plate counts (CFU), which is time consuming. Use OD, which is an indirect proxy.

Use cells/mL, which is the direct cell count.

Assess growth rate in different media 💡 Insight 🌿 Growth

Assess carrying capacity in different media 💡 Insight 🌿 Growth

Optimize harvest point ⚙️ Optimization 🌽 Harvest

TODO

Get X % better yield/titer

Decide when to harvest during a cultivation ⚙️ Optimization 🌽 Harvest

Predict when to harvest during a production ⏲️️ Prediction 🌽 Harvest

Just a couple of initial measurements predict the optimal harvest time for the batch

Assess onset and conclusion of sporulation 💡 Insight 🌽 Harvest

Consistent bacterial cell banking

Design seed train

Optimize feed profile in fed-batch

Assess exact number of doublings in CRISPRi workflows

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