Why use BactoBox®
The short answer: Because BactoBox® measures real bacterial growth. No proxies. No guesswork.
BactoBox® helps whether you are trying to:
BactoBox® fits into all key steps in your upstream bioprocess: 🌱 Seed, 🌿 growth, and 🌽 harvest.
With and without BactoBox®
Once you use BactoBox® in your workflows, it's easy to forget what life was like before. This table serves as a reminder.
Optimize starter culture ⚙️ Optimization 🌱 Seed
TODO
One-shot setup of high quality culture (OptiSeeding)
Inoculate an overnight culture ⚙️ Optimization 🌱 Seed
Track growth curve 💡 Insight 🌿 Growth
Use plate counts (CFU), which is time consuming. Use OD, which is an indirect proxy.
Use cells/mL, which is the direct cell count.
Assess growth rate in different media 💡 Insight 🌿 Growth
Assess carrying capacity in different media 💡 Insight 🌿 Growth
Optimize harvest point ⚙️ Optimization 🌽 Harvest
TODO
Get X % better yield/titer
Decide when to harvest during a cultivation ⚙️ Optimization 🌽 Harvest
Predict when to harvest during a production ⏲️️ Prediction 🌽 Harvest
Just a couple of initial measurements predict the optimal harvest time for the batch
Assess onset and conclusion of sporulation 💡 Insight 🌽 Harvest
Consistent bacterial cell banking
Design seed train
Optimize feed profile in fed-batch
Assess exact number of doublings in CRISPRi workflows
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